Methacrylic Acid Copolymer

Leading Manufacturers, Wholesaler and Trader of E-100 Basic Butylated Methacrylate Copolymer, L-100 Methacrylic Acid Copolymer Powder, L100-55 Methacrylic Acid Copolymer Powder, L30D Liquid Methacrylic Acid Copolymer and S100 Methacrylic Acid Copolymer Powder from Gandhinagar.

2,200.00 - 2,400.00 / Kilogram

25 Kilogram (MOQ)

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Business Type Manufacturer, Supplier, Trader
Country of Origin India,Made in India
E-100 Granules
Color Colorless to Yellowish Granules
Type Pharma Grade
Material Dry Place below 45 Degree C
Brand Spcoat E-100
Product Code 24938-16-7
Payment Terms L/C, D/P, T/T, Western Union
Delivery Time 1 week
Packaging Details 25 kg fiber durms packing

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carrier for amorphous solid dispersions, coating, film former, Moisture protection, odor masking, protection against degradation, Solubility enhancement, swallowability enhancement, Taste masking

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550.00 / Kilogram

20 Kilogram (MOQ)

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Business Type Manufacturer, Supplier
Material Enteric Coating Material In Pharmaceutical Formulations
Type Pharma Grade
Usage Pharmaceutical Industry
Country of Origin Made In India
Purity 99%
Form Powder
Color White
Brand Name L-100
CAS No. 25086-15-1
Other Names METHACRYLIC ACID-METHYL METHACRYLATE COPOLYMER (1:1)
Product Code 25086-15-1
Payment Terms L/C, D/A, D/P, T/T, Western Union
Delivery Time 3 Days
Packaging Details 20 Kgs and 25 Kgs in Fiber Durm with LDPE liner bag

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L 100 are anionic copolymers based on methacrylic acic and methyl methacrylate. Physical properties: It is a solid substance in form of a white powder with a faint characteristic odour. Characteristics: Effective and stable enteric coatings with a fast dissolution in the upper Bowel.

Physiological concepts of the gastrointestinal absorption
The digestive tube in humans, usually called the gastrointestinal (GI) tract, is a long tube of 10–12 m that begins in the mouth, extend to the anus, and can be divided into the mouth, the esophagus, the stomach, the small intestine and the large intestine. This, along with the salivary glands, liver and pancreas, forms part of the digestive system, whose function is the processing of food and the facilitation of nutrient incorporation to the rest of the body.
The GI tract consists of four
Enteric coating and its function
The enteric coating is an outer coating that can be used in oral pharmaceutical dosage forms, and is usually made up of synthetic polymers or natural products. There are numerous possible motivations for using enteric coating, including altering the odor or taste of the drug adding protection against environmental conditions (especially pH), the protection of gastric mucosa against the irritating action of some drugs or allowing for site or time specific drug release (Shokri and Adibkia, 2013).
 
Kinds of polymers for enteric coating
The usual polymers used in enteric coatings have carboxylic groups in their composition and their solubility depends on the number of carboxylic groups they contain. Enteric coating polymers may be grouped according to their chemical composition.
Coating process
There are four basic methods for coating solids for the purpose of control drug release: pan coating using solvent evaporation, fluidized-bed coating using solvent evaporation, compaction coating and hot melt coating (Mathiowitz, 1999). In addition to these, other coating methods include microencapsulation, electrostatic coating and 3D printing coating (Wang and Shmeis, 2005).
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1,050.00 - 1,200.00 / Kilogram

10 Kilogram (MOQ)

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Business Type Manufacturer, Supplier
Brand Name Spcoat L-100-55,Spcoat L100-55
Texture White ,free-flowing powder
Color White
Form Powder
Usage Pharma Coating POlymer,Pharmaceutical Industry
Purity 99%
Grade Standard Reagent Grade
Packaging Type Wooden Box, Plastic Drums, Fiber Durm Packing
Packaging Size 10 Kg
Type Enteric Coating,Pharma Grade
Shelf Life 5 Years
Composition L100–55 is an anionic copolymer polymer consisting of methacrylic acid and ethyl acrylate
Country of Origin India,Made In India
Soluable In Water Yes
Cas Number 25212-88-8
Material White Powder
Product Code 25212-88-8
Payment Terms L/C, D/A, D/P, T/T, Western Union
Delivery Time 3 Days
Packaging Details 10 kgs Fiber Durm

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"l 100 55" refers to  L 100-55, a functional polymer used in pharmaceuticals for enteric coatingIt is a pH-dependent copolymer that dissolves at a pH above 5.5.
L 100-55 is commonly used to protect drugs from acidic environments in the stomach and allows for controlled release in the intestines. 
 
Here's a more detailed breakdown:
 L 100-55:
  • This is a specific type of a family of polymers used in pharmaceutical coatings.
  • pH-dependent:
    The polymer's solubility and dissolution are influenced by the pH of the surrounding environment.
  • Enteric coating:
    It's designed to prevent drug release in the stomach (acidic environment) and release it in the intestines (higher pH).
  • Applications:
    L 100-55 is used for various purposes, including:
    • Film coating: To create a barrier around tablets, capsules, or other oral dosage forms.
    • Drug release control: To prevent immediate release of drugs and to target release in specific areas of the digestive tract.
    • Solubility enhancement: In some cases, it can be used to enhance the solubility of certain drugs.
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101.00 / Kilogram

60 Kilogram (MOQ)

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Business Type Manufacturer, Supplier
Country of Origin India,Made In India
Shelf Life 2Year
Type Aqueous Film Coating
Packaging Size 60 Kg
Packaging Type Plastic Drums, Plastic Can
Grade Standard Industrial Grade
Purity 99%
Usage Pharma Coating POlymer,Pharmaceutical Industry
Form Milky White Liquid
Color White,Milky White Aqueous
Texture Milky White Liquid
Material AQUEOUS DISPERSION 30 %,METHACRYLIC ACID – ETHYL ACRYLATE COPOLYMER (1:1
Brand Name L-30 D METHACRYLIC ACID – ETHYL ACRYLATE COPOLYMER (1:1)
CAS No. 25212-88-8
pH Value 2.0 to 3.0
Cas Number 25212-88-8
Product Code 25212-88-8
Payment Terms L/C, D/A, D/P, T/T
Delivery Time 3 Days
Packaging Details 60 KGS HDPE WHITE CARBOYS

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L30D is a 30% aqueous dispersion of methacrylic acid-ethyl acrylate copolymer, used as an enteric coating for tablets and other pharmaceutical applications. It is designed to dissolve at a pH of 5.5 or above, making it suitable for delayed release in the upper intestine. 
Key Features and Applications:
  • pH-Responsive:
    L30D is insoluble in acidic environments (like the stomach) but becomes soluble in the more alkaline environment of the small intestine. 
    Enteric Coating:
  • It's primarily used to create a coating that protects drugs from degradation in the stomach and allows them to be released in the intestine. 
     
  • Other Applications:
    Beyond enteric coatings, it can be used in other pharmaceutical applications, such as controlled-release formulations and site-specific drug delivery.
    Versatile:
  • L30D can be used with various tablet formulations, including tablets, capsules, and multiparticulates
     
    How it Works:
  1. 1. Coating:
    L30D is applied as a dispersion to the drug substance (e.g., tablet, capsule).
    2. In Stomach:
  2. The coating remains intact in the stomach's acidic environment due to the insoluble nature of L30D at low pH.
     
    3. In Intestine:
  3. As the tablet reaches the small intestine, the higher pH (5.5 or above) causes the L30D coating to dissolve, releasing the drug. 
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580.00 / Kilogram

10 Kilogram (MOQ)

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Business Type Manufacturer, Supplier
Brand Name S-100 Methacrylic acid - methyl methacrylate copolymer (1:2)
Material White Powder
Color White,White Powder
Form Powder
Grade Standard Pharma Grade
Packaging Type Fiber Durm Packing
Packaging Size 0-25Kg
Type Enteric Coating,Enteric Coating Polymer
Shelf Life 5 Years
Country of Origin India,Made in India
CAS No. 25086-15-1
Purity 99%
Usage Enteric Coating Polymer
Product Code 25086-15-1
Payment Terms L/C, D/A, D/P, T/T
Delivery Time 3 Days
Packaging Details 20 Kgs Fiber Durm Packing with LDPE LIner Bag

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Methacrylic acid - methyl methacrylate copolymer (1:2), also known as methacrylic acid copolymer, Type B - NF, is an excipient used in pharmaceutical is a solid white powder with dissolution above pH of 7.0, and is used in enteric coatings for fast dissolution in the upper bowel, for granulation of drug substances in powder form for controlled-release, and for site-specific drug delivery. It is typically released in the upper bowel of the gastrointestinal tract.

S-100 is a commercially available methacrylic acid - methyl methacrylate copolymer with a ratio of 1:2. It is a white powder that is water-insoluble but dissolves above a pH of 7.0.
 S-100 is widely used as a pharmaceutical excipient, particularly in enteric coatings, due to its ability to dissolve in the small intestine. It is also used for granulation and taste masking.
Copolymer Composition:
  • S-100 is a copolymer, meaning it's a polymer made from two different monomers: methacrylic acid and methyl methacrylate. The ratio of these monomers is 1:2. 
     
    Pharmaceutical Applications:
    • Enteric Coatings: S-100's ability to dissolve in the small intestine makes it ideal for enteric coatings, which protect drugs from the stomach's acidic environment and ensure they dissolve in the upper intestine. 
       
    • Granulation: It can be used in the granulation of powder drugs for controlled-release formulations
    • Taste Masking: S-100 can be used to mask the taste of unpleasant drugs. 
    • Other Uses:
  • While primarily used in pharmaceuticals, S-100 may have other applications, such as in coatings and adhesives.
     
    Physical Properties:
  • S-100 is a white, free-flowing powder that is insoluble in water but dissolves in solutions above pH 7.0. 
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